Innovation in a drop, perfected for safety

Our filler platform couples physical and chemical bonding for a Complex Crosslinking Technology. It amplifies the strengths of biphasic and monophasic designs, delivering low modification (low crosslink ratio) with high cohesiveness and elasticity while maintaining smooth injectability.

Biphasic hyaluronic acid filler

With small amounts of crosslinker and high HA load, it achieves low cohesiveness and high G’. BDDE is about 1–2 mol%, and purification reduces free BDDE to below 2 ppm. Performance is comparable to leading products in this class.

Monophasic hyaluronic acid filler

Using lower HA content with higher crosslinker, it forms a cohesive elastic gel. Free BDDE is reduced to < 2 ppm; linker and pendant BDDE remain about 7–14 mol% for safety. Representative examples include Juvederm, Chaeum, and Nuramis.

CCT Process

Longevity from nature, safety through science

The first commercial spherical HA filler, engineered for implantation with both safety and duration. It offers strong volume and aesthetics with tunable persistence via CCT, maintaining volume stability for 2+ years.

Key features

Promotes collagen, provides dual-volume effect, and shows low immune stimulation. High enzymatic stability supports long-lasting outcomes, offering over 5× higher enzyme stability than conventional HA fillers.

Pipeline using SFT

The first thermo-responsive long-acting HA bead filler

Commercialized thermo-responsive spherical filler. Low viscoelasticity at room temperature for easy injection, then higher viscoelasticity at body temperature for stability. Delivers effects for up to 2 years with over 5× enzyme stability vs. conventional fillers.